What GPU do you need to run Qwen 2.5 VL 72B?
72.7B params 128K max context VisionTool use
The smallest GPU memory that runs Qwen 2.5 VL 72B well is 64 GB (Q4_K_M, e.g. RTX Spark). 18 of 132 GPUs run it well and 4 more are a tight fit.
MMLU 86.1
VRAM needed per quantization
| Quantization | Weights | 16K context | 32K context | Full 128K |
|---|---|---|---|---|
| Q4_K_M | 47.4 GB | 52.3 GB | 57.2 GB | 86.4 GB |
| Q8_0 | 77.3 GB | 82.2 GB | 87.1 GB | 116.3 GB |
Weights plus fp16 KV cache. Leave ~1 GB headroom for the inference engine.
Cheapest GPUs that can run Qwen 2.5 VL 72B
Lowest launch MSRP among GPUs that run its smallest quantization (Q4_K_M) well, with at least 16K context.
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GPUs that can run Qwen 2.5 VL 72B
Best quantization that fits on each GPU, with the context and speed it gets. For chips with several memory sizes, the smallest that works is shown.
NVIDIA
- L40S 48 GB Q4_K_M 1K context · ~18 tok/s tight fit
- RTX 6000 Ada 48 GB Q4_K_M 1K context · ~20 tok/s tight fit
- RTX A6000 48 GB Q4_K_M 1K context · ~16 tok/s tight fit
- RTX PRO 5000 Blackwell 48 GB Q4_K_M 1K context · ~28 tok/s tight fit
- RTX Spark 64 GB Q4_K_M 54K context · ~6 tok/s
- RTX PRO 5000 Blackwell 72GB 72 GB Q4_K_M 80K context · ~28 tok/s
- RTX PRO 5500 Blackwell 84 GB Q8_0 21K context · ~18 tok/s
- RTX PRO 6000 Blackwell 96 GB Q8_0 61K context · ~23 tok/s
- DGX Spark (GB 10) 128 GB Q8_0 128K context · ~3 tok/s
AMD
- Ryzen AI Max (Strix Halo) 64 GB Q4_K_M 54K context · ~5 tok/s
- Ryzen AI Max 400 (Gorgon Halo) 64 GB Q4_K_M 54K context · ~6 tok/s
Apple
- M1 Max 64 GB Q4_K_M 54K context · ~8 tok/s
- M1 Ultra 64 GB Q4_K_M 54K context · ~17 tok/s
- M2 Max 64 GB Q4_K_M 54K context · ~8 tok/s
- M2 Ultra 64 GB Q4_K_M 54K context · ~17 tok/s
- M3 Max 64 GB Q4_K_M 54K context · ~8 tok/s
- M4 Max 64 GB Q4_K_M 54K context · ~11 tok/s
- M4 Pro 64 GB Q4_K_M 54K context · ~6 tok/s
- M5 Max 64 GB Q4_K_M 54K context · ~13 tok/s
- M5 Pro 64 GB Q4_K_M 54K context · ~6 tok/s
- M3 Ultra 96 GB Q8_0 61K context · ~10 tok/s
- M5 Ultra 96 GB Q8_0 61K context · ~15 tok/s